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Radiation Biology Research
Faculty:   
Chuan-Yuan Li:   
 Dewhirst | Jirtle | Li | Poulson | Vujaskovic | Counter | Yao
 Education and Training | Selected Publications


    1.
    Li, C-Y., Yandell, D.W., and Little, J.B.(1992) Molecular Mechanisms of Spontaneous and Induced Loss of Heterozygosity in Human Cells In Vitro. Somatic Cell and Molecular Genetics, 18: 77-87

    2.
    Li, C-Y., Yandell, D.W., and Little, J.B. (1992) Evidence for Coincident Mutations in Human Lymphoblast Clones Selected for Functional Loss of a Thymidine Kinase Gene. Molecular Carcinogenesis, 5:270-277

    3. Spiro, I. J., Yandell, D.W., Li, C-Y. , Saini, S., Ferry, J., Powelson J., Katkov, W.N., and Cosimi, A.B (1993). Lymphoma of Donor Origin Occuring at the Porta Hepatis of Transplanted Liver. New England Journal of Medicine, 329:27-29

    4. Poremba, C., Dockhorn-Dworniczak, B., Merrit, V., Li, C-Y. (1993) Heidle, G., Tauber, P., Bocker, W., , and Yandell, D.W. Immature Teratomas of Different Origin Carried by a Pregnant Mother and Her Fetus. Diagnostic Molecular Pathology , 2:131-136

    5. Li, C-Y., Yandell, D.W., and Little, J.B. (1994) Elevated frequency of Microsatellite Mutations in Human Lymphoblast Clones Selected for Mutations at Thymidine Kinase locus. Molecular & Cellular Biology , 14:4373-4379

    6. Li, C-Y., Nagasawa, H., Tsang, N., and Little, J.B. (1995) Radiation-Induced Irreversible G0/G1 Block is Abolished in Human Diploid Fibroblasts Transfected with the Human Papilloma Virus E6 gene: Implication of the p53-Cip1/WAF1 pathway. International Journal of Oncology, 1 : 223-236

    7. Li, C-Y., Suardet, L., and Little, J.B. (1995) Potential Role of WAF1/Cip1/p21 as a Mediator of TGF-b Cytoinhibitory Effect . Journal of Biological Chemistry 270:4971-4974

    8. Nagasawa, H., Li, C-Y., Maki, C.G. , Imrich A. and Little, J.B. (1995) Relationship between Radiation-Induced G1 Phase Arrest and p53 Function in Human Tumor Cells Cancer Research 55:1842-1846.

    9. Little, J.B. , Nagasawa, H., Keng, P., and Li, C-Y. Absence of Radiation-induced G1-arrest in Two Closely Related Human Lymphoblast Cell Lines That Differ in p53 Status Journal of Biological Chemistry 270:11033-11036.

    10. Tsang, N., Nagasawa, H., Li, C-Y., and Little, J.B. Abrogation of p53 function by Transfection of HPV16 E6 Gene Enhances the Resistance of Human Diploid Fibroblasts to Ionizing Radiation Oncogene 10:2403-2408.

    11. Li, C-Y., Nagasawa, H., Dahlberg, W.A., and Little, J.B. (1995) Published Capacity for p53 in Mediating a Radiation-Induced G1 Arrest in Established Human Tumor Cell Lines Oncogene :1885-1892.

    12. Little, J.B., Li, C-Y., Nagasawa, H., Pfenning, T., and Vetrovs, H. Genomic Instability and Radiation Mutagenesis (1996) J. Chimie Phys. 93:157-164

    13. Li, C-Y., Nagasawa, H., Dahlberg, W.A., and Little, J.B. (1996) The Role of Tumor Suppressor Genes in Determining a Radation-induced G1-arrest and Human Cell Carcinogenesis Radiation Oncology Investigations, 3:268-271.

    14. Huang, H-M., Li, C-Y, Little, J.B. (1996) Abrogation of p53 Function in Human Tumor Cells Does Not Alter Their Sensitivity to Ionizing Radiation. International Journal of Radiation Biology, 70:151-160.

    15. Suardet, L., Li, C-Y., and Little J.B. (1996) Radio-induced modulation of transforming growth factor sensitivity in a p53 wild-type human colorectal cancer cell line . International Journal of Cancer 68:126-31.

    16. Yu, Y., Li, C-Y., Little, J.B. (1997) Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblastoid cells. Oncogene, 14:1661-1667.

    17. Huang, Q., Shan, S, Braun, R.D., Lanzen, J., Anyrhambatla, G., Kong, G., Borelli, M., Corry, P., Dewhirst, M.W., and Li, C-Y. (1999) GFP based non-invasive, in vivo monitoring of gene expression. Nature Biotechnology, 17: 1033-1035.

    18. Li, C-Y., Shan, SQ., Huang, Q., Braun, R.D., Lanzen, J., Turnage, J., Dewhirst, M.W. (2000) Initial stages of tumor cells-induced angiogenesis:evaluation via skin window chambers in rodent models Journal of the National Cancer Institute, 92:143-127

    19. Huang,Q., Hu, K., Lohr, F., Zhang,L., Braun, R., Lanzen, J., Little,JB., Dewhirst, MW., and Li, C-Y. (2000) Heat-induced Gene Expression as a Novel Targeted Cancer Gene Therapy Strategy Cancer Research, In Press.


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